Understanding nicotine’s paradoxical effects and prevention strategies The Science of Vaping Fatigue Does vaping make you tired despite nicotine being a stimulant? Research reveals this paradox stems from nicotine’s dual-phase impact: initial stimulation followed by neurotransmitter depletion that disrupts sleep architecture . Canadian vapers report 38% higher fatigue rates than non-users due to: REM sleep suppression:Nicotine reduces […]